The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
In 2019–2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent
of a several acute respiratory infection named COVID-19, which is causing a worldwide
pandemic. There are still many unresolved questions regarding the pathogenesis of this
disease and especially the reasons underlying the extremely different clinical course,
ranging from asymptomatic forms to severe manifestations, including the Acute Respiratory
Distress Syndrome (ARDS). SARS-CoV-2 showed phylogenetic similarities to both SARS …