[PDF][PDF] Neuropharmacology of quinolinic and kynurenic acids.

TW Stone - Pharmacological reviews, 1993 - researchgate.net
Pharmacological reviews, 1993researchgate.net
Although kynurenic acid was recognised long ago as a tryptophan metabolite in canine
urine (Ellinger, 1904), it was not until about 1947 that the kynurenine pathway was
recognised as a major route for the conversion of tryptophan to nicotinamide and its
nucleotide conjugates (Beadle et a!., 1947). It was some years later that quinolinic acid was
accepted as an intermediate(Gholson et
Although kynurenic acid was recognised long ago as a tryptophan metabolite in canine urine (Ellinger, 1904), it was not until about 1947 that the kynurenine pathway was recognised as a major route for the conversion of tryptophan to nicotinamide and its nucleotide conjugates (Beadle et a!., 1947). It was some years later that quinolinic acid was accepted as an intermediate(Gholson et
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