The immune landscape of human tumors: Implications for cancer immunotherapy
G Bindea, B Mlecnik, HK Angell, J Galon - Oncoimmunology, 2014 - Taylor & Francis
G Bindea, B Mlecnik, HK Angell, J Galon
Oncoimmunology, 2014•Taylor & FrancisUnderstanding the spontaneous immune response of cancer patients is critical for the
design of efficient anticancer immunotherapies. The power of integrative tumor immunology
approaches allowed for a comprehensive view of the immune system evolution in the course
of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune
cells are spatiotemporally regulated, a finding that has profound implications for the
development of efficient anticancer immunotherapies.
design of efficient anticancer immunotherapies. The power of integrative tumor immunology
approaches allowed for a comprehensive view of the immune system evolution in the course
of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune
cells are spatiotemporally regulated, a finding that has profound implications for the
development of efficient anticancer immunotherapies.
Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune cells are spatiotemporally regulated, a finding that has profound implications for the development of efficient anticancer immunotherapies.
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