[HTML][HTML] Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients

M Ollero, G Astarita, IC Guerrera… - Journal of lipid …, 2011 - ASBMB
Cystic fibrosis (CF) is associated with abnormal lipid metabolism. We have recently shown
variations in plasma levels of several phosphatidylcholine (PC) and lysophopshatidylcholine
(LPC) species related to disease severity in CF patients. Here our goal was to search for
blood plasma lipid signatures characteristic of CF patients bearing the same mutation
(F508del) and different phenotypes, and to study their correlation with forced expiratory
volume in 1 s (FEV1) and Pseudomonas aeruginosa chronic infection, evaluated at the time …