Pseudomembranous colitis: report of a severe case with unusual clinical signs in a young nurse

A Boaz, M Dan, I Charuzi, O Landau, Y Aloni… - Diseases of the colon & …, 2000 - Springer
A Boaz, M Dan, I Charuzi, O Landau, Y Aloni, S Kyzer
Diseases of the colon & rectum, 2000Springer
We describe the case of a young and otherwise healthy nurse who developed
pseudomembranous colitis ten days after receiving oral clindamycin for dental infection. Her
clinical course was particularly stormy and was characterized by severe diarrhea and
vomiting, profuse ascites, pleural effusion, abdominal tenderness, peritoneal irritation, and
systemic toxicity. The Clostridium difficile assay was negative on two occasions. Features
compatible with pseudomembranous colitis were seen at sigmoidoscopy, and the diagnosis …
Abstract
We describe the case of a young and otherwise healthy nurse who developed pseudomembranous colitis ten days after receiving oral clindamycin for dental infection. Her clinical course was particularly stormy and was characterized by severe diarrhea and vomiting, profuse ascites, pleural effusion, abdominal tenderness, peritoneal irritation, and systemic toxicity. TheClostridium difficile assay was negative on two occasions. Features compatible with pseudomembranous colitis were seen at sigmoidoscopy, and the diagnosis was confirmed by biopsies.
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