Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease

PC Harris, KT Bae, S Rossetti, VE Torres… - Journal of the …, 2006 - journals.lww.com
Data from serial renal magnetic resonance imaging of the Consortium of Radiologic Imaging
Study of PKD (CRISP) autosomal dominant polycystic kidney disease (PKD) population
showed that cystic expansion occurs at a consistent rate per individual, although it is
heterogeneous in the population, and that larger kidneys are associated with more rapid
disease progression. The significance of gene type to disease progression is analyzed in
this study of the CRISP cohort. Gene type was determined in 183 families (219 cases); 156 …