Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis
LA van Vught, PMCK Klouwenberg, C Spitoni… - Jama, 2016 - jamanetwork.com
Importance Sepsis is considered to induce immune suppression, leading to increased
susceptibility to secondary infections with associated late mortality. Objective To determine
the clinical and host genomic characteristics, incidence, and attributable mortality of
intensive care unit (ICU)–acquired infections in patients admitted to the ICU with or without
sepsis. Design, Setting, and Participants Prospective observational study comprising
consecutive admissions of more than 48 hours in 2 ICUs in the Netherlands from January …
susceptibility to secondary infections with associated late mortality. Objective To determine
the clinical and host genomic characteristics, incidence, and attributable mortality of
intensive care unit (ICU)–acquired infections in patients admitted to the ICU with or without
sepsis. Design, Setting, and Participants Prospective observational study comprising
consecutive admissions of more than 48 hours in 2 ICUs in the Netherlands from January …