Deficits in neuronal function are a hallmark of spinal cord injury (SCI) and therapeutic efforts
are often focused on central nervous system (CNS) axon regeneration. However, secondary
injury responses by astrocytes, microglia, pericytes, endothelial cells, Schwann cells,
fibroblasts, meningeal cells, and other glia not only potentiate SCI damage but also facilitate
endogenous repair. Due to their profound impact on the progression of SCI, glial cells and
modification of the glial scar are focuses of SCI therapeutic research. Within and around the …