The increasing number of population-based and epidemiologic associations between
oxidant pollutant exposures and cardiopulmonary disease exacerbation, decrements in
pulmonary function, and mortality underscores the important detrimental effects of oxidants
on public health. Because inhaled oxidants initiate a number of pathologic processes,
including inflammation of the airways, which may contribute to the pathogenesis and/or
exacerbation of airways disease, it is critical to understand the mechanisms through which …