[HTML][HTML] Orthogonal comparison of molecular signatures of kidney transplants with subclinical and clinical acute rejection: equivalent performance is agnostic to both …
We performed orthogonal technology comparisons of concurrent peripheral blood and
biopsy tissue samples from 69 kidney transplant recipients who underwent comprehensive
algorithm-driven clinical phenotyping. The sample cohort included patients with normal
protocol biopsies and stable transplant (sTx) function (n= 25), subclinical acute rejection
(subAR, n= 23), and clinical acute rejection (cAR, n= 21). Comparisons between microarray
and RNA sequencing (RNA-seq) signatures were performed and demonstrated a strong …
biopsy tissue samples from 69 kidney transplant recipients who underwent comprehensive
algorithm-driven clinical phenotyping. The sample cohort included patients with normal
protocol biopsies and stable transplant (sTx) function (n= 25), subclinical acute rejection
(subAR, n= 23), and clinical acute rejection (cAR, n= 21). Comparisons between microarray
and RNA sequencing (RNA-seq) signatures were performed and demonstrated a strong …