Intracellular bacteria in placental basal plate localize to extravillous trophoblasts
B Cao, IU Mysorekar - Placenta, 2014 - Elsevier
We previously showed that intracellular bacteria are present in the human placental
maternal–fetal interface (basal plate). To determine the bacterial niche, basal plate biopsies
were 1) examined histologically, and 2) cultured ex vivo, infected with either gram negative
(Escherichia coli) or positive (Listeria monocytogenes) bacteria, and examined by
histological staining, immunofluorescence, and transmission electron microscopy. We found
bacteria in fetal extravillous trophoblasts (EVTs) in basal plate biopsies. Both E. coli and L …
maternal–fetal interface (basal plate). To determine the bacterial niche, basal plate biopsies
were 1) examined histologically, and 2) cultured ex vivo, infected with either gram negative
(Escherichia coli) or positive (Listeria monocytogenes) bacteria, and examined by
histological staining, immunofluorescence, and transmission electron microscopy. We found
bacteria in fetal extravillous trophoblasts (EVTs) in basal plate biopsies. Both E. coli and L …