[HTML][HTML] p38-2, a novel mitogen-activated protein kinase with distinct properties
B Stein, MX Yang, DB Young, R Janknecht… - Journal of Biological …, 1997 - ASBMB
Mitogen-activated protein (MAP) kinases are involved in many cellular processes. Here we
describe the cloning and characterization of a new MAP kinase, p38-2. p38-2 belongs to the
p38 subfamily of MAP kinases and shares with it the TGY phosphorylation motif. The
complete p38-2 cDNA was isolated by polymerase chain reaction. It encodes a 364-amino
acid protein with 73% identity to p38. Two shorter isoforms missing the phosphorylation motif
were identified. Analysis of various tissues demonstrated that p38-2 is differently expressed …
describe the cloning and characterization of a new MAP kinase, p38-2. p38-2 belongs to the
p38 subfamily of MAP kinases and shares with it the TGY phosphorylation motif. The
complete p38-2 cDNA was isolated by polymerase chain reaction. It encodes a 364-amino
acid protein with 73% identity to p38. Two shorter isoforms missing the phosphorylation motif
were identified. Analysis of various tissues demonstrated that p38-2 is differently expressed …
