[HTML][HTML] Role of toll-like receptors in multiple myeloma and recent advances

KK Thakur, NB Bolshette, C Trandafir… - Experimental …, 2015 - Elsevier
Highlights•Toll-like receptors are key components in inflammatory processes•Toll-like
receptor activation stimulates cell proliferation in chronic inflammation•We hypothesize that
toll-like receptor activation might trigger and maintain multiple myeloma•We believe that
ongoing and future Toll-like receptor–based therapies could treat multiple myelomaMultiple
myeloma (MM) is a hematologic malignancy characterized as an abnormal proliferation and
invasion of plasma cells into the bone marrow. Toll-like receptors (ТLRs) connect the innate …