Autonomic neurotransmission: 60 years since sir Henry Dale
G Burnstock - Annual Review of Pharmacology and Toxicology, 2009 - annualreviews.org
In the early twentieth century, Sir Henry Dale and others described brilliant studies of
autonomic neurotransmission utilizing acetylcholine and noradrenaline. However, within the
past 60 years, new discoveries have changed our understanding of the organization of the
autonomic nervous system, including the structure and function of the nonsynaptic
autonomic neuroeffector junction, the multiplicity of neurotransmitters, cotransmission,
neuromodulation, dual control of vascular tone by perivascular nerves and endothelial cells …
autonomic neurotransmission utilizing acetylcholine and noradrenaline. However, within the
past 60 years, new discoveries have changed our understanding of the organization of the
autonomic nervous system, including the structure and function of the nonsynaptic
autonomic neuroeffector junction, the multiplicity of neurotransmitters, cotransmission,
neuromodulation, dual control of vascular tone by perivascular nerves and endothelial cells …
