The immune response modifier resiquimod mimics CD40-induced B cell activation
GA Bishop, LM Ramirez, M Baccam, LK Busch… - Cellular …, 2001 - Elsevier
Members of the imidazoquinoline molecule family, including imiquimod and resiquimod (R-
848), have potent antiviral and antitumor activities. Imiquimod cream (5%)(Aldara) is
currently indicated for treatment of external genital and perianal warts. Previous
characterization of these compounds has focused upon their ability to activate monocytes
and dendritic cells, but recent studies have shown that resiquimod also stimulates B
lymphocytes to proliferate and express an activated phenotype. This suggests that …
848), have potent antiviral and antitumor activities. Imiquimod cream (5%)(Aldara) is
currently indicated for treatment of external genital and perianal warts. Previous
characterization of these compounds has focused upon their ability to activate monocytes
and dendritic cells, but recent studies have shown that resiquimod also stimulates B
lymphocytes to proliferate and express an activated phenotype. This suggests that …