[HTML][HTML] Cloning and expression of human core 1 β1, 3-galactosyltransferase

T Ju, K Brewer, A D'Souza, RD Cummings… - Journal of Biological …, 2002 - ASBMB
The common core 1 O-glycan structure Galβ1→ 3GalNAc-R is the precursor for many
extended mucin-type O-glycan structures in animal cell surface and secreted glycoproteins.
Core 1 is synthesized by the transfer of Gal from UDP-Gal to GalNAcα1-R by core 1 β3-
galactosyltransferase (core 1 β3-Gal-T). Amino acid sequences from purified rat core 1 β3-
Gal-T (Ju, T., Cummings, RD, and Canfield, WM (2002) J. Biol. Chem. 277, 169–177) were
used to identify the core 1 β3-Gal-T sequences in the human expressed sequence tag data …