[HTML][HTML] Robust label-free, quantitative profiling of circulating plasma microparticle (MP) associated proteins
S Braga-Lagache, N Buchs, MI Iacovache… - Molecular & cellular …, 2016 - ASBMB
Cells of the vascular system release spherical vesicles, called microparticles, in the size
range of 0.1–1 μm induced by a variety of stress factors resulting in variable concentrations
between health and disease. Furthermore, microparticles have intercellular communication/
signaling properties and interfere with inflammation and coagulation pathways. Today's
most used analytical technology for microparticle characterization, flow cytometry, is lacking
sensitivity and specificity, which might have led to the publication of contradicting results in …
range of 0.1–1 μm induced by a variety of stress factors resulting in variable concentrations
between health and disease. Furthermore, microparticles have intercellular communication/
signaling properties and interfere with inflammation and coagulation pathways. Today's
most used analytical technology for microparticle characterization, flow cytometry, is lacking
sensitivity and specificity, which might have led to the publication of contradicting results in …