[HTML][HTML] Proteome analysis of human neutrophil granulocytes from patients with monogenic disease using data-independent acquisition*[S]
Neutrophil granulocytes are critical mediators of innate immunity and tissue regeneration.
Rare diseases of neutrophil granulocytes may affect their differentiation and/or functions.
However, there are very few validated diagnostic tests assessing the functions of neutrophil
granulocytes in these diseases. Here, we set out to probe omics analysis as a novel
diagnostic platform for patients with defective differentiation and function of neutrophil
granulocytes. We analyzed highly purified neutrophil granulocytes from 68 healthy …
Rare diseases of neutrophil granulocytes may affect their differentiation and/or functions.
However, there are very few validated diagnostic tests assessing the functions of neutrophil
granulocytes in these diseases. Here, we set out to probe omics analysis as a novel
diagnostic platform for patients with defective differentiation and function of neutrophil
granulocytes. We analyzed highly purified neutrophil granulocytes from 68 healthy …