P-selectin–deficient mice to study pathophysiology of sickle cell disease
MF Bennewitz, E Tutuncuoglu, S Gudapati… - Blood …, 2020 - ashpublications.org
MF Bennewitz, E Tutuncuoglu, S Gudapati, T Brzoska, SC Watkins, SP Monga…
Blood advances, 2020•ashpublications.orgP-selectin–deficient mice to study pathophysiology of sickle cell disease | Blood Advances |
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Key Points
- P-selectin–deficient SCD mice are protected from lung vaso-occlusion.
- P-selectin–deficient SCD mice will be useful in assessing the benefits of anti–P-selectin therapy in diverse complications of SCD.
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