Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion

JSY Tan, CJP Seow, VJ Goh, DL Silver - Journal of Genetics and Genomics, 2014 - Elsevier
Lipid droplets (LDs) were once viewed as simple, inert lipid micelles. However, they are now
known to be organelles with a rich proteome involved in a myriad of cellular processes. LDs
are heterogeneous in nature with different sizes and compositions of phospholipids, neutral
lipids and proteins. This review takes a focused look at the roles of proteins involved in the
regulation of LD formation, expansion, and morphology. The related proteins are
summarized such as the fat-specific protein (Fsp27), fat storage-inducing transmembrane …