Effects of angiotensin-converting enzyme inhibition on glomerular capillary wall ultrastructure in MWF/Ztm rats.

BE Iordache, O Imberti, C Foglieni… - Journal of the …, 1994 - journals.lww.com
Previous studies have documented that treatment with angiotensin-converting enzyme
(ACE) inhibitors prevents spontaneous proteinuria and enhances the glomerular
ultrafiltration coefficient in male MWF/Ztm rats. The aim of this study was to study whether
these beneficial effects of ACE inhibitors on glomerular capillary wall function are derived
from the preservation of its ultrastructure. Conventional morphometrical analysis of kidney
tissue, by light and electron microscopy, was used to quantify glomerular structural changes …