Management of sepsis in patients with liver failure

JM Canabal, DJ Kramer - Current opinion in critical care, 2008 - journals.lww.com
JM Canabal, DJ Kramer
Current opinion in critical care, 2008journals.lww.com
Much has been advanced in the field of sepsis management. Understanding the
pathophysiology of liver dysfunction and decompensation of a diseased liver incites
questions for future research. Early goal-directed therapy, lactate clearance, glycemic
control, low volume ventilation strategies, nutrition, adrenal insufficiency, renal dysfunction,
hepatorenal syndrome prevention and treatment are some of the issues in the management
of sepsis, with or without liver disease, that are relevant in this review.
Summary
Much has been advanced in the field of sepsis management. Understanding the pathophysiology of liver dysfunction and decompensation of a diseased liver incites questions for future research. Early goal-directed therapy, lactate clearance, glycemic control, low volume ventilation strategies, nutrition, adrenal insufficiency, renal dysfunction, hepatorenal syndrome prevention and treatment are some of the issues in the management of sepsis, with or without liver disease, that are relevant in this review.
Lippincott Williams & Wilkins