The importance of blood platelet lipid signaling in thrombosis and in sepsis

FV Bounes, A Mujalli, C Cenac, S Severin… - Advances in biological …, 2018 - Elsevier
Blood platelets are the first line of defense against hemorrhages and are also strongly
involved in the processes of arterial thrombosis, a leading cause of death worldwide.
Besides their well-established roles in hemostasis, vascular wall repair and thrombosis,
platelets are now recognized as important players in other processes such as inflammation,
healing, lymphangiogenesis, neoangiogenesis or cancer. Evidence is accumulating they
are key effector cells in immune and inflammatory responses to host infection. To perform …