Adipocytes anatomically associated with lymph nodes (and omental milky spots) have many
special properties including fatty acid composition and the control of lipolysis that equip
them to interact locally with lymphoid cells. Lymph node lymphocytes and tissue dendritic
cells acquire their fatty acids from the contiguous adipocytes. Lymph node-derived dendritic
cells suppress lipolysis in perinodal adipocytes but those that permeate the adipose tissue
stimulate lipolysis, especially after minor, local immune stimulation. Inflammation alters the …