Understanding lymphangiogenesis in knockout models, the cornea, and ocular diseases for the development of therapeutic interventions
JF Yang, A Walia, Y Huang, K Han, MI Rosenblatt… - Survey of …, 2016 - Elsevier
A major focus of cancer research for several decades has been understand the ability of
tumors to induce new blood vessel formation, a process known as angiogenesis.
Unfortunately, only limited success has been achieved in the clinical application of
angiogenesis inhibitors. We now know that lymphangiogenesis, the growth of lymphatic
vessels, likely also plays a major role in tumor progression. Thus, therapeutic strategies
targeting lymphangiogenesis or both lymphangiogenesis and angiogenesis may represent …
tumors to induce new blood vessel formation, a process known as angiogenesis.
Unfortunately, only limited success has been achieved in the clinical application of
angiogenesis inhibitors. We now know that lymphangiogenesis, the growth of lymphatic
vessels, likely also plays a major role in tumor progression. Thus, therapeutic strategies
targeting lymphangiogenesis or both lymphangiogenesis and angiogenesis may represent …