Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis

IT De Almeida, H Cortez-Pinto, G Fidalgo, D Rodrigues… - Clinical nutrition, 2002 - Elsevier
Background and aim: Non-alcoholic steatohepatitis (NASH), the association of steatosis with
an inflammatory response, is a novel liver disease of unknown pathogenesis and prognosis.
Triacylglycerols and their precursors, the fatty acids, are the likely candidates to accumulate
in the hepatocyte. Disturbed fatty acid metabolism can be involved in the pathogenesis of
NASH but there is no information concerning its plasma fatty acid profile. The aim of this
study was to evaluate plasma total (esterified plus free) and free fatty acids concentrations to …