IL-10, an inflammatory/inhibitory cytokine, but not always
IL-10 has been previously called cytokine synthesis inhibiting factor, produced mostly by
Th2 cells, macrophages and CD8+ cell clones. IL-10 is capable of inhibiting the synthesis of
several cytokines from different cells, antigen or mitogen activated. IL-10 exerts its inhibition
at the mRNA transcriptional and translational level. In addition, IL-10 is a co-stimulatory
cytokine on activated T cells. For example, IL-10 inhibits NK cell activity, the production of
Th1 cytokines, cytokines generated by peripheral blood mononuclear cells, and …
Th2 cells, macrophages and CD8+ cell clones. IL-10 is capable of inhibiting the synthesis of
several cytokines from different cells, antigen or mitogen activated. IL-10 exerts its inhibition
at the mRNA transcriptional and translational level. In addition, IL-10 is a co-stimulatory
cytokine on activated T cells. For example, IL-10 inhibits NK cell activity, the production of
Th1 cytokines, cytokines generated by peripheral blood mononuclear cells, and …