Preferential distribution of apoptotic bodies in acinar zone 3 of normal human and rat liver

A Benedetti, AM Jézéquel, F Orlandi - Journal of hepatology, 1988 - Elsevier
The aim of the present investigation was to study the number and acinar distribution of
apoptotic bodies in normal liver as an approach to a better understanding of cell kinetics in
the hepatic parenchyma. The material included 20 normal human needle liver biopsies and
20 normal male Sprague-Dawley rats. For each liver sample, the following parameters were
measured: number of apoptotic bodies in the lobule, topographical localization, and
distance from terminal hepatic veins (THV), ie, the row of hepatocytes concerned, H1 being …