Fetal valproate syndrome and autism: additional evidence of an association
G Williams, J King, M Cunningham… - … medicine and child …, 2001 - cambridge.org
G Williams, J King, M Cunningham, M Stephan, B Kerr, JH Hersh
Developmental medicine and child neurology, 2001•cambridge.orgAutism has been described in association with a variety of medical and genetic conditions.
We previously reported on a patient whose clinical phenotype was compatible with both fetal
valproate syndrome (FVS) and autism. Here we present five additional patients with FVS
and autism. In all five of our patients, there was evidence of cognitive deficits, manifestations
of autism, and typical phenotypic characteristics of FVS. The association between this known
teratogen and autism has both clinical and research implications.
We previously reported on a patient whose clinical phenotype was compatible with both fetal
valproate syndrome (FVS) and autism. Here we present five additional patients with FVS
and autism. In all five of our patients, there was evidence of cognitive deficits, manifestations
of autism, and typical phenotypic characteristics of FVS. The association between this known
teratogen and autism has both clinical and research implications.
Autism has been described in association with a variety of medical and genetic conditions. We previously reported on a patient whose clinical phenotype was compatible with both fetal valproate syndrome (FVS) and autism. Here we present five additional patients with FVS and autism. In all five of our patients, there was evidence of cognitive deficits, manifestations of autism, and typical phenotypic characteristics of FVS. The association between this known teratogen and autism has both clinical and research implications.
Cambridge University Press