[HTML][HTML] Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of …
CA Moxon, NV Chisala, R Mzikamanda… - Journal of Thrombosis …, 2015 - Elsevier
Background A procoagulant state is implicated in cerebral malaria (CM) pathogenesis, but
whether disseminated intravascular coagulation (DIC) is present or associated with a fatal
outcome is unclear. Objectives To determine the frequency of overt DIC, according to ISTH
criteria, in children with fatal and non‐fatal CM. Methods/patients Malawian children were
recruited into a prospective cohort study in the following diagnostic groups: retinopathy‐
positive CM (n= 140), retinopathy‐negative CM (n= 36), non‐malarial coma (n= 14) …
whether disseminated intravascular coagulation (DIC) is present or associated with a fatal
outcome is unclear. Objectives To determine the frequency of overt DIC, according to ISTH
criteria, in children with fatal and non‐fatal CM. Methods/patients Malawian children were
recruited into a prospective cohort study in the following diagnostic groups: retinopathy‐
positive CM (n= 140), retinopathy‐negative CM (n= 36), non‐malarial coma (n= 14) …