Influence of cold ischemia time on complement activation, neopterin, and cytokine release in liver transplantation

A Schmidt, H Tomasdottir, A Bengtsson - Transplantation proceedings, 2004 - Elsevier
OBJECTIVES: The aim of this study was to determine whether a cold ischemia time (CIT) of>
12 hours influences the activation of complement as well as the plasma concentrations of
neopterin, interleukin (IL)-6, or IL-8 in orthotopic liver transplantation (OLT). PATIENTS AND
METHODS: Eighteen consecutive patients undergoing OLT using a veno-venous bypass
technique were divided into 2 groups: duration of CIT> 12 hours (group 1; n= 11), and CIT<
12 hours (group 2; n= 7). Blood samples were drawn preoperatively, 1 minute before, and …