Key histopathologic features of liver biopsies that distinguish biliary atresia from other causes of infantile cholestasis and their correlation with outcome: a multicenter …
P Russo, JC Magee, RA Anders, KE Bove… - The American journal …, 2016 - journals.lww.com
The liver biopsy guides diagnostic investigation and therapy in infants with undiagnosed
cholestasis. Histologic features in the liver may also have prognostic value in the patient with
biliary atresia (BA). We assessed the relative value of histologic features in 227 liver needle
biopsies in discriminating between BA and other cholestatic disorders in infants enrolled in a
prospective Childhood Liver Disease Research Network (ChiLDReN) cohort study by
correlating histology with clinical findings in infants with and without BA. In addition, we …
cholestasis. Histologic features in the liver may also have prognostic value in the patient with
biliary atresia (BA). We assessed the relative value of histologic features in 227 liver needle
biopsies in discriminating between BA and other cholestatic disorders in infants enrolled in a
prospective Childhood Liver Disease Research Network (ChiLDReN) cohort study by
correlating histology with clinical findings in infants with and without BA. In addition, we …