Biliary atresia and other cholestatic childhood diseases: advances and future challenges
HJ Verkade, JA Bezerra, M Davenport… - Journal of …, 2016 - Elsevier
Biliary Atresia and other cholestatic childhood diseases are rare conditions affecting the
function and/or anatomy along the canalicular-bile duct continuum, characterised by onset of
persistent cholestatic jaundice during the neonatal period. Biliary atresia (BA) is the most
common among these, but still has an incidence of only 1 in 10–19,000 in Europe and North
America. Other diseases such as the genetic conditions, Alagille syndrome (ALGS) and
Progressive Familial Intrahepatic Cholestasis (PFIC), are less common. Choledochal …
function and/or anatomy along the canalicular-bile duct continuum, characterised by onset of
persistent cholestatic jaundice during the neonatal period. Biliary atresia (BA) is the most
common among these, but still has an incidence of only 1 in 10–19,000 in Europe and North
America. Other diseases such as the genetic conditions, Alagille syndrome (ALGS) and
Progressive Familial Intrahepatic Cholestasis (PFIC), are less common. Choledochal …
