Function of CD80 and CD86 on monocyte-and stem cell-derived dendritic cells

S Dilioglou, JM Cruse, RE Lewis - Experimental and molecular pathology, 2003 - Elsevier
Dendritic cells (DCs) consist of a heterogeneous population of hematopoietic cells
characterized by their unique dendritic morphology, their efficient antigen-presenting
capability to activate naïve CD4+ and CD8+ T cells, as well as their lack of lineage-specific
markers. Functional properties comparing umbilical cord blood monocyte-derived and
umbilical cord blood stem cell-derived DCs have not yet been investigated. Human umbilical
cord blood CD14+ monocytes and CD34+ stem cells were induced to differentiate into …