[HTML][HTML] Composite 'thymoheart'transplantation improves cardiac allograft survival
MT Menard, ML Schwarze, JS Allan… - American Journal of …, 2004 - Elsevier
We have generated a novel composite organ, the thymoheart, which facilitates the
contemporaneous transfer of fully vascularized and functional donor thymic tissue to the host
at the time of cardiac transplantation. Composite thymoheart allografts were prepared in
MHC-inbred miniature swine by implanting autologous thymic tissue into donor hearts 60–
90 days before organ procurement. Thymoheart allografts and unmanipulated control hearts
were then transplanted into three groups, each treated with the same 12 days of …
contemporaneous transfer of fully vascularized and functional donor thymic tissue to the host
at the time of cardiac transplantation. Composite thymoheart allografts were prepared in
MHC-inbred miniature swine by implanting autologous thymic tissue into donor hearts 60–
90 days before organ procurement. Thymoheart allografts and unmanipulated control hearts
were then transplanted into three groups, each treated with the same 12 days of …