Coronary sinus neuropeptide Y levels and adverse outcomes in patients with stable chronic heart failure
OA Ajijola, NA Chatterjee, MJ Gonzales… - JAMA …, 2020 - jamanetwork.com
Importance Chronic heart failure (CHF) is associated with increased sympathetic drive and
may increase expression of the cotransmitter neuropeptide Y (NPY) within sympathetic
neurons. Objective To determine whether myocardial NPY levels are associated with
outcomes in patients with stable CHF. Design, Setting, and Participants Prospective
observational cohort study conducted at a single-center, tertiary care hospital. Stable
patients with heart failure undergoing elective cardiac resynchronization therapy device …
may increase expression of the cotransmitter neuropeptide Y (NPY) within sympathetic
neurons. Objective To determine whether myocardial NPY levels are associated with
outcomes in patients with stable CHF. Design, Setting, and Participants Prospective
observational cohort study conducted at a single-center, tertiary care hospital. Stable
patients with heart failure undergoing elective cardiac resynchronization therapy device …