Bursting enables GRP neurons to engage spinal itch circuits

H Petitjean, P Séguéla, R Sharif-Naeini - Neuron, 2019 - cell.com
Neuron, 2019cell.com
Bursting Enables GRP Neurons to Engage Spinal Itch Circuits: Neuron Skip to Main Content
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In this issue of Neuron, Pagani et al. (2019) find that itch signaling occurs only when GRP neurons fire action potentials in bursts. This enables GRP release and the activation of GRPR neurons, which help carry the itch signal to the brain.
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