Mas-related G protein–coupled receptors and the biology of itch sensation
J Meixiong, X Dong - Annual review of genetics, 2017 - annualreviews.org
Chronic, persistent itch is a devastating symptom that causes much suffering. In recent
years, there has been great progress made in understanding the molecules, cells, and
circuits underlying itch sensation. Once thought to be carried by pain-sensing neurons, itch
is now believed to be capable of being transmitted by dedicated sensory labeled lines.
Members of the Mas-related G protein–coupled receptor (Mrgpr) family demarcate an itch-
specific labeled line in the peripheral nervous system. In the spinal cord, the expression of …
years, there has been great progress made in understanding the molecules, cells, and
circuits underlying itch sensation. Once thought to be carried by pain-sensing neurons, itch
is now believed to be capable of being transmitted by dedicated sensory labeled lines.
Members of the Mas-related G protein–coupled receptor (Mrgpr) family demarcate an itch-
specific labeled line in the peripheral nervous system. In the spinal cord, the expression of …