[HTML][HTML] Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)-and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue …
Y Cho, BC Hazen, AP Russell, A Kralli - Journal of Biological Chemistry, 2013 - ASBMB
Mitochondrial oxidative metabolism and energy transduction pathways are critical for
skeletal and cardiac muscle function. The expression of genes important for mitochondrial
biogenesis and oxidative metabolism are under the control of members of the peroxisome
proliferator-activated receptor γ coactivator 1 (PGC-1) family of transcriptional coactivators
and the estrogen-related receptor (ERR) subfamily of nuclear receptors. Perturbations in
PGC-1 and/or ERR activities have been associated with alterations in capacity for …
skeletal and cardiac muscle function. The expression of genes important for mitochondrial
biogenesis and oxidative metabolism are under the control of members of the peroxisome
proliferator-activated receptor γ coactivator 1 (PGC-1) family of transcriptional coactivators
and the estrogen-related receptor (ERR) subfamily of nuclear receptors. Perturbations in
PGC-1 and/or ERR activities have been associated with alterations in capacity for …