Abstract Interleukin (IL)-15, a member of the immunoregulatory cytokines family, is a
pluripotent molecule with therapeutic potential. It is predominantly expressed by the myeloid
cells, as well as other cell types. IL-15 serves multiple functions including dictating T cell
response, regulating tissue repair and B cell homing, modulating inflammation, and
activating NK cells. Among cytokines, IL-15 is unique because of its wide expression, tightly
regulated secretion, trans-presentation, and therapeutic potential. IL-15 has been …