Steele: Influences of Glucose Loading 42 1 cose, have concluded that the value of V does not change to an important extent during insulin action. Of the other letters appearing in FIGURE 1, A, represents the total number of microcuries of CI4 glucose in the pool at time t, R1, and R2 the amount (grams) of glucose carbon per minute entering and leaving the pool at time t, and F the amount of CI4 glucose (“weightless” amount) in microcuries per minute being given by constant infusion (F is zero in those experiments called “single injection” experiments). The specific activity of the glucose in the compartment may be designated it and is equal to the ratio