[HTML][HTML] Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle

H Lu, CW Stratton, YW Tang - Journal of medical virology, 2020 - ncbi.nlm.nih.gov
Journal of medical virology, 2020ncbi.nlm.nih.gov
Since December 2019, a total of 41 cases of pneumonia of unknown etiology have been
confirmed in Wuhan city, Hubei Province, China. Wuhan city is a major transportation hub
with a population of more than 11 million people. Most of the patients visited a local fish and
wild animal market last month. At a national press conference held today, Dr Jianguo Xu, an
academician of the Chinese Academy of Engineering, who led a scientific team announced
that a new‐type coronavirus, tentatively named by World Health Organization as the 2019 …
Since December 2019, a total of 41 cases of pneumonia of unknown etiology have been confirmed in Wuhan city, Hubei Province, China. Wuhan city is a major transportation hub with a population of more than 11 million people. Most of the patients visited a local fish and wild animal market last month. At a national press conference held today, Dr Jianguo Xu, an academician of the Chinese Academy of Engineering, who led a scientific team announced that a new‐type coronavirus, tentatively named by World Health Organization as the 2019‐new coronavirus (2019‐nCoV), had caused this outbreak. 1 The 2019‐nCoV has a different coronavirus‐specific nucleic acid sequence from known human coronavirus species, which are similar to some of the beta coronaviruses identified in bats. 2, 3 The virus‐specific nucleic acid sequences were detected in lung fluid, blood and throat swab samples in 15 patients and the virus that was isolated showed a typical coronavirus appearance under electron microscopy. Further research will be conducted to better understand the new coronavirus to develop antiviral agents and vaccines. 4
We applauded the excellent job that has been done so far. The infection was first described in December. Within 9 days, a special team consisted of physicians, scientists and epidemiologists who ruled out several extremely contagious pathogens including SARS, which killed hundreds of people more than a decade ago, and MERS. This has surely alleviated environmental concerns as Hong Kong authorities had quickly stepped up the disinfection of trains and airplanes and checks of passengers due to this outbreak. Most of the patients visited the fish and wild animal market last month in Wuhan. This fish and wild animal market also sold live animals such as poultry, bats, marmots, and snakes. All patients received prompt supportive treatment in quarantine. Among them, seven patients were in
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