Fanconi anemia (FA) is an autosomal and X-linked recessive disorder characterized by
bone marrow failure, acute myelogenous leukemia, solid tumors, and developmental
abnormalities. Recent years have seen a dramatic improvement in FA patient treatment,
resulting in a greater survival of children into adulthood. These improvements have been
made despite the fact that a definitive cellular function for the proteins in the FA pathway has
yet to be elucidated. Delineating the cellular functions of the FA pathway could help further …