[HTML][HTML] Pancreas 3D organoids: current and future aspects as a research platform for personalized medicine in pancreatic cancer
L Moreira, B Bakir, P Chatterji, Z Dantes… - Cellular and molecular …, 2018 - Elsevier
L Moreira, B Bakir, P Chatterji, Z Dantes, M Reichert, AK Rustgi
Cellular and molecular gastroenterology and hepatology, 2018•ElsevierPancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the
third leading cause of cancer-related mortality in the United States. Although important
advances have been made in the last decade, the mortality rate of pancreatic ductal
adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging
model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful
tool for several applications, but above all, representing a step toward personalized …
third leading cause of cancer-related mortality in the United States. Although important
advances have been made in the last decade, the mortality rate of pancreatic ductal
adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging
model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful
tool for several applications, but above all, representing a step toward personalized …
Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.
Elsevier