Decreased T-cell repertoire diversity in sepsis: a preliminary study
F Venet, O Filipe-Santos, A Lepape, C Malcus… - Critical care …, 2013 - journals.lww.com
Objective: Septic syndromes are the leading causes of mortality in intensive care units. In
patients, the occurrence of sepsis-induced immune suppression is associated with delayed
mortality, although the exact role of lymphocyte dysfunctions is not well established. The
objective of this study was to investigate T-cell receptor diversity, an important feature of T-
cell response, in patients with septic shock. Design: Preliminary prospective observational
study. Setting: Adult intensive care units in a university hospital. Subjects: Patients with …
patients, the occurrence of sepsis-induced immune suppression is associated with delayed
mortality, although the exact role of lymphocyte dysfunctions is not well established. The
objective of this study was to investigate T-cell receptor diversity, an important feature of T-
cell response, in patients with septic shock. Design: Preliminary prospective observational
study. Setting: Adult intensive care units in a university hospital. Subjects: Patients with …
