The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study
RS Stern, PFU Study - Journal of the American Academy of Dermatology, 2012 - Elsevier
BACKGROUND: By 1977, psoralen and ultraviolet A (PUVA) was established as a highly
effective therapy for psoriasis. Because of concerns about potential long-term adverse
effects, particularly cancer, the PUVA Follow-Up Study was established to assess long-term
risk and benefits of PUVA. OBJECTIVE: We sought to determine the association of certain
squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) risk with exposure to
PUVA. METHODS: For nearly 30 years, this prospective cohort study of 1380 patients with …
effective therapy for psoriasis. Because of concerns about potential long-term adverse
effects, particularly cancer, the PUVA Follow-Up Study was established to assess long-term
risk and benefits of PUVA. OBJECTIVE: We sought to determine the association of certain
squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) risk with exposure to
PUVA. METHODS: For nearly 30 years, this prospective cohort study of 1380 patients with …
