Familial skin cancer syndromes: Increased risk of nonmelanotic skin cancers and extracutaneous tumors

PD Jaju, KJ Ransohoff, JY Tang, KY Sarin - Journal of the American …, 2016 - Elsevier
Nonmelanoma skin cancers (NMSCs) represent the most common malignancies worldwide,
with reported incidence rising each year. Both cutaneous squamous cell carcinoma (SCC)
and basal cell carcinoma (BCC), as well as other NMSCs, represent complex diseases with
a combination of environmental and genetic risk factors. In general, hereditary cancer
syndromes that increase the risk of NMSC fall under several broad categories: those
associated with immunodeficiencies, those that affect skin pigmentation, and those that …