The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility …
MCJ Roex, L Hageman, MT Heemskerk, SAJ Veld… - Cytotherapy, 2018 - Elsevier
Background Adoptive transfer of donor-derived T cells can be applied to improve immune
reconstitution in immune-compromised patients after allogeneic stem cell transplantation.
The separation of beneficial T cells from potentially harmful T cells can be achieved by using
the major histocompatibility complex (MHC) I-Streptamer isolation technology, which has
proven its feasibility for the fast and pure isolation of T-cell populations with a single
specificity. We have analyzed the feasibility of the simultaneous isolation of multiple antigen …
reconstitution in immune-compromised patients after allogeneic stem cell transplantation.
The separation of beneficial T cells from potentially harmful T cells can be achieved by using
the major histocompatibility complex (MHC) I-Streptamer isolation technology, which has
proven its feasibility for the fast and pure isolation of T-cell populations with a single
specificity. We have analyzed the feasibility of the simultaneous isolation of multiple antigen …