Safety and efficacy of pembrolizumab monotherapy in patients with previously treated advanced gastric and gastroesophageal junction cancer: phase 2 clinical …
Importance Therapeutic options are needed for patients with advanced gastric cancer
whose disease has progressed after 2 or more lines of therapy. Objective To evaluate the
safety and efficacy of pembrolizumab in a cohort of patients with previously treated gastric or
gastroesophageal junction cancer. Design, Setting, and Participants In the phase 2, global,
open-label, single-arm, multicohort KEYNOTE-059 study, 259 patients in 16 countries were
enrolled in a cohort between March 2, 2015, and May 26, 2016. Median (range) follow-up …
whose disease has progressed after 2 or more lines of therapy. Objective To evaluate the
safety and efficacy of pembrolizumab in a cohort of patients with previously treated gastric or
gastroesophageal junction cancer. Design, Setting, and Participants In the phase 2, global,
open-label, single-arm, multicohort KEYNOTE-059 study, 259 patients in 16 countries were
enrolled in a cohort between March 2, 2015, and May 26, 2016. Median (range) follow-up …