[HTML][HTML] FOXP3 and NFAT: partners in tolerance
AY Rudensky, M Gavin, Y Zheng - Cell, 2006 - cell.com
AY Rudensky, M Gavin, Y Zheng
Cell, 2006•cell.comRegulatory T cells suppress autoimmune responses to self-antigens. Recent studies,
including one in this issue of Cell (Wu et al., 2006), suggest that the ability of T cells to
choose between launching a productive immune response, functional inactivation, or
developing into regulatory T cells depends upon the interplay of the key transcriptional
regulators FOXP3 and NFAT.
including one in this issue of Cell (Wu et al., 2006), suggest that the ability of T cells to
choose between launching a productive immune response, functional inactivation, or
developing into regulatory T cells depends upon the interplay of the key transcriptional
regulators FOXP3 and NFAT.
Regulatory T cells suppress autoimmune responses to self-antigens. Recent studies, including one in this issue of Cell (Wu et al., 2006), suggest that the ability of T cells to choose between launching a productive immune response, functional inactivation, or developing into regulatory T cells depends upon the interplay of the key transcriptional regulators FOXP3 and NFAT.
cell.com